Hotel Sedgewick is named after Henry Sidgwick and Charles Sidgwick Minot. A very Aykroyd thing to do.
What indicated this?
Aykroyd has stated that he based Ghostbusters on an article on quantum mechanics and parapsychology he read in the American Society for Psychical Research about how apparitional experiences (the actual term used by real parapsychologists to refer to what we call ghosts) may manifest themselves in the real world.
In this interview right at the beginning he states this.
https://youtu.be/2Bl1MmSgPAc
In the next interview he lists the title of the article too at 1:25s, beware it's a long title.
https://youtu.be/R7HSgi_k5rY
Also 03:07s in this video
https://youtu.be/ec5lB0zNWJE
Also in the above video at 04:50s he goes into full Ray Stantz mode, it's like you're watching a deleted scene from the original GB 1984.
So the ASPR is pretty important in the mythology of Ghostbusters. So much so that I believe Erin Gilbert had ASPR certificates in her office in ATC as easter eggs.
Henry Sidgwick was the 1st president of the original Society for Psychical Research when it was formed in the UK in 1882.
The unrelated Charles Sidgwick Minot was founder of the American version of the SPR, the ASPR, two years later in 1884.
Considering that both unrelated founders are called Sidgwick, the renaming of the Biltmore hotel to Sedgewick hotel is beyond a coincidence in my view.
The latter is just a more contemporary (to 1984) version of the original 19th century name.