This issue is part of a consecutive three-issue run adapting Ghostbusters II for a comics audience:
Throughout all three parts, the creative team remained consistent: writer James Van Hise, penciler John Tobias, inker Rich Rankin, colorist Suzanne Dechnik, letterer Dan Nakrosis, art director Michele Mach, editor Katherine Llewellyn, and chief editor Tony Caputo.
Part 3 adapts the second half of the Ghostbusters II film, drawing from chapters 18 through 28 of the shooting script. The adapted segments cover:
One deleted scene from the script, "Louis' Cousin, Sherman Tully," is also adapted, introducing Sherman Tully as a minor character. Like Part 2, this issue draws on a script draft that included material cut from the finished film.
During production of this final part, the story's ending was revised. Four pages were deleted or substantially altered so the conclusion would align with the theatrical version of the film rather than the script draft.
The altered story retains the core film ending: the Ghostbusters, Dana Barrett, Oscar, and Janosz Poha emerge from the museum after defeating Vigo. Louis Tully is dropped off at the museum by Slimer and finds everyone safe. Jack Hardemeyer is freed from the Wall of Slime, his attitude improved by the mood slime.
The issue then includes scenes not in the film: after the New Year's Eve celebration, Jack and the Ghostbusters discuss the displaced Statue of Liberty, and the Ghostbusters present Jack with their bill for the job. Peter Venkman notes that the city stiffed them last time around. The final pages show the Ghostbusters, Dana, and Oscar attending the official reopening of the Statue of Liberty on Liberty Island some weeks after the events of New Year's Eve, where the group discusses their personal heritages.
Minor: Slimed Restaurant Patron, Maitre D', Restaurant Cops (2), Gracie Mansion Butler, Mayor Lenny, Orderly No. 1, Psychiatric Doctor, Sherman Tully, Plaza Hotel Man, Woman with Fur Coat, Mink Coat, Doorman, Detectives (2), Police Sergeant, Police Lieutenant, Dock Supervisor, the Titanic, Fire Captain, the Statue of Liberty
