Ectotron arrives on Earth and discovers a situation far more complex than he anticipated. Recognizing the need for backup, he calls in Optimus Prime. While waiting for Optimus to arrive, Ectotron accompanies the Ghostbusters on a ghost bust, getting firsthand experience with paranormal investigation. Back at the Firehouse, the team deals with the continuing presence of Starscream's ghost. The issue ends with Optimus Prime making his entrance and encountering some unwanted graffiti from local vandals.
Ghostbusters equipment appearing in this issue includes the Proton Pack and Particle Thrower, the P.K.E. Meter, the Ghost Trap, the Paranormal Containment Research Tank, the Wall-Trap (last seen in Ghostbusters Get Real #3), and a Proton Grenade, which Janine keeps in her desk drawer. On the Transformers side, the Autobot spacecraft The Ark is referenced in this issue (with a printing error cutting off the "T" in "The Ark," later corrected in the collected trade paperback).
Cover development for this issue began more than eight months before publication. Tom Waltz posted rough cover thumbnail sketches on December 11, 2018, with more finished versions following on December 28, 2018. A work-in-progress teaser of the Firehouse appeared January 29, 2019. An edited version of Dan Schoening's connected covers for the full mini-series was revealed February 18, 2019.
Philip Murphy revealed his variant cover on May 24, 2019. Subsequent social media previews included Ectotron and Ray Stantz in the Firehouse garage (May 29), a panel of Ectotron and Ray fist-bumping (June 3), and a panel of Starscream and Slimer (June 17). Cover A was revealed in its entirety on June 26, 2019.
In the weeks before and after the August 7 release date, Luis Antonio Delgado and Dan Schoening shared a series of unlettered panel previews on social media, covering scenes with Ectotron and Janine, Peter trapping Starscream, Optimus Prime and Wheeljack, Starscream and Slimer, Ectotron transforming into Ecto-1, and the Ghostbusters taking on the Electric Ghost.
This issue is densely packed with cross-franchise and production references:
