When the animals at the Central Park Zoo begin speaking and demanding their freedom, New York City faces a supernatural crisis unlike any other.1 Egon Spengler and the Extreme Ghostbusters rush to the scene, unaware that one creature is orchestrating a larger scheme: using possession to drive the zoo's animals to attack humanity in revenge for their captivity. The story is set in 1997, both the broadcast year and the in-universe setting of the Extreme Ghostbusters series.2
Supporting: Nervous Nelly, Frankie, Len, and the human form of Le Maison from the Extreme Ghostbusters episode "Home is Where the Horror Is" (page 2). Peter Venkman appears in a surprise cameo at the Firehouse, wearing the suit from The Real Ghostbusters episode "The Collect Call of Cathulhu." A purified Vigo tapestry and a framed portrait of Dana Barrett are visible in the background of that scene.1
Antagonist: Animal Possessors, led by an unidentified entity.
The Extreme Ghostbusters deploy Proton Packs (including Proton Pistols and Proton Canisters), a P.K.E. Meter, Ghost Traps, and a flashlight.1 Roland's flashlight is the same model used in The Real Ghostbusters episode "The Grundel."
The story moves through the Central Park Zoo, the Firehouse, the New York City Public Library, and a bar called the Nut House. The New York Public Library's banner displays the years 1911 and 1997: the Main Branch dedication ceremony was held on May 23, 1911,3 and 1997 is the in-universe year of Extreme Ghostbusters.2 Egon also references the Containment Unit during the investigation.1
The issue's development was documented through a series of social media posts by the creative team and editorial staff over several months:
Cover A (Tim Lattie) features Egon Spengler and Janine Melnitz alongside a 1997-updated Tobin's Spirit Guide, the Extreme Ghostbusters' equipment, the Kenner Firehouse set, Ecto-1, the Trendmaster Ghost Blastin' Buster Bike, and a gallery of ghosts including the Spawn of Achira, Boney, Eyeball, Flyer, Gremlin, Sylphon, Slimer, and Pagan.1
Cover RI (Anthony Marques, J. Bone) places Slimer alongside the full Extreme Ghostbusters team. The group's staging and poses are loosely based on the ending of the Extreme Ghostbusters title sequence and character designer Fil Barlow's title artwork.1
Cover RE (Dan Schoening and Luis Antonio Delgado) is a dense ensemble piece featuring Gu Mo, Achira and her spawn, Duophanes in his true form, the Vathek (Crainiac, Corpuscle, and Gristle), Piper, Ravana, Slimer, Kahlil, a donkey ghost, a Leprechaun, the Jersey Devil, Ecto-1, and the full Extreme Ghostbusters team. Its staging also references the Extreme Ghostbusters title sequence.1
Some content on this page was researched using the Ghostbusters Wiki on Fandom.
Spook Central, "Extreme Ghostbusters Episode Guide," accessed 2026-06-13, https://www.spookcentral.us/sclib/extreme-ghostbusters-episode-guide.html. "This follow-up to The Real Ghostbusters consists of forty 30-minute episodes that aired in syndication from September 1, 1997 to December 8, 1997."
"New York Public Library Main Branch," Wikipedia, accessed 2026-06-13, https://en.wikipedia.org/wiki/New_York_Public_Library_Main_Branch. The official dedication ceremony presided over by President William Howard Taft was held on May 23, 1911; the building opened to the general public on May 24, 1911.
Matthew 6:28, The Holy Bible (King James Version). "Consider the lilies of the field, how they grow; they toil not, neither do they spin."
"Milli Vanilli," Wikipedia, accessed 2026-06-13, https://en.wikipedia.org/wiki/Milli_Vanilli. Milli Vanilli was a pop duo from Munich, Germany, founded in 1988 by producer Frank Farian, combining pop, R&B, and dance music.
