Continued directly from Issue #7, the assembled Ghostbusters face Tiamat in the Collectors' Limbo. Winston Zeddemore negotiates with the goddess, reminding her that the research Kylie Griffin uncovered during the Mass Hysteria arc established that a god could be appeased with a sacrifice to leave a dimension. The teams deploy seven Trap-Gates simultaneously against Tiamat, far exceeding the six that Egon of Dimension 68-R had stated would be insufficient for a Class 7, and manage to confine her. Winston elects to leave Tiamat sealed in a Trap rather than deposit her into the Containment Unit, echoing his handling of the main antagonist in the TMNT/Ghostbusters crossover.
Back at the Firehouse, the teams celebrate their return. Egon Spengler uses his subliminal messaging code (first introduced in the ongoing series) to trigger the Chicken Dance in Egon of Dimension 68-E. Ray Stantz worries they have been gone for months due to the time-distorting nature of the Collectors' dimension, but the absence turns out to be brief. The celebration is cut short when Jenny Moran, warned in Issue #6 by Rachel Unglighter, is attacked by a ghost and pulled into the Containment Unit, setting up the next story arc. Meanwhile, Walter Peck meets Janine Melnitz at a Pequod's to renew the offer he made in Issue #1.
The issue features an unusually wide array of ghost-hunting hardware drawn from multiple continuities:
Cover A (Dan Schoening and Luis Antonio Delgado): Features Prime Egon Spengler, Melanie Ortiz, Peter Venkman, and Ecto-1, alongside the Ghostbusters of Dimension 35-N and Kevin Beckman of Dimension 80-C. Dan Schoening posted the full Kevin Beckman image used for this cover on November 11, 2018.
Cover B (Tim Lattie): A large ensemble cover featuring Prime Cait Banner, Zoe Zawadzki, Janine Melnitz, Ray Stantz, Egon Spengler, Peter Venkman, and Jenny Moran alongside Mike the Golem and Robo-Buster of Dimension 68-V; Ray Stantz of Dimension 68-R; Eduardo Rivera and Garrett Miller of Dimension 68-E; Erin Gilbert of Dimension 80-C; and Alan Crendall and Samuel Hazer of Dimension 50-S. Ray and Egon wear the charcoal flightsuits from Ghostbusters II; Janine wears her first-film outfit; Ray holds the Giga Meter. The cover vehicle and motorcycle are based on 1986 Kenner concept art.
Cover RI (Luca Pizzari, Retailer Incentive): Features Prime Ecto-1, the Firehouse, Winston, and Slimer alongside Kylie Griffin of Dimension 68-E, Alan Crendall of Dimension 50-S, and Jillian Holtzmann of Dimension 80-C. A preview of this cover was posted by Tom Waltz on March 14, 2018. Note: Issue #7 mistakenly previewed the Cover RI rather than Cover A on page 22.